@Aaron N, I have not used any Hodgdon powders with the 8X68s. But I will share what my experience has been with loading for it.
I think any of the 4350 powders will work well with 180gr and lighter bullets. I haven’t messed much with 190 - 200g bullets but think the 4350s' will do well there too. I use VVN550, RL-16 and IMR4350 for 180g (TSX) and 160g (TTSX)bullets. I seem to get best accuracy and speed with 68.5g of powder. I would start around 64.0g and work my way up.
For 220g - 250g I use Alliants 4000MR. It is, I think, slightly slower than RL-19 which should work well too. With these bullet weights and powders I would start at 63.0g and work up.
All of my bullet seating has been 3.425” o.a.l. except for the 250gr Woodleigh which is 3.54”. My rifle is a Blaser R8 and is somewhat long throated.
Hope this helps.