Yes. I had a buddy that bought one last year in 375H&H and I mounted a Trijicon 1-6 on it for him. Medium rings should've been sufficient, but we had to go up to the super high rings to clear the bolt. Other than that issue, the gun is a tack driver and a pleasure to shoot.
Pic is the medium rings and as you can see it is very tight. However, when you would crank it up to 6x, the bolt would hit.