I think you meant RL15, not 17. 70.0 grains of RL15 and a 300 grain bullet is a pretty common load for an H&H. I imagine it’d be pretty close for the Ruger as well.I'm going to echo the "start low and work up". I have never used 760 as RL17 is pretty much the king for the .375 H&H/Ruger. That said, I don't chase half inch groups or max velocity with mine. I just find a middle-of-the-road load that doesn't beat the gun up and expands out to my maximum shooting range. The .375 will kill game really well even at reduced load.