@jjrckd
Well, living on the West coast of Norway we hardly never (if even ever) experience weather which even comes close to the coldest winter day in Africa
Well I'd say so.......
I'm certainly not implying one needs to be as anal retentive as I admittedly am when it comes to reloading, but certainly I have noticed pressure signs before in hot weather with some of my rounds that were fine in cooler weather. Most noticeably in a custom 338 Winchester Magnum I own. That rifle is primarily an elk, moose, caribou, etc. rifle and utilized in much cooler and damper weather, probably very similar to your climate. The rounds were initially loaded hot, and during the summer months when shooting it, I noticed flattened primers and a slightly sticky bolt handle when lifting the bolt handle on ejection. This load was developed by the rifle builder. I chose to back off by o.5 grains of powder, and have not noticed the phenomena again.
I think at the distances the 404 Jeffery would be utilized at (150 m and in), there would be very little difference in point of impact between your climate and in Africa. More importantly, is not to "hot-rod" the round and risk sticking a bolt when using the rifle for dangerous game. It's just not necessary to get great performance from this old stalwart. As you probably know, originally W.J. Jeffery and Co. wanted a round that would function in a bolt action rifle, and also duplicate the performance of the venerable rimmed double rifle cartridge 450/400 3 inch. The original velocities were targeted for around 2125 fps if I recall correctly. The 400 grain bullet at that velocity was very effective at its intended purpose, so much so that the game departments of Northern and Southern Rhodesia, Kenya, and Tanzania supplied their game wardens with Vickers rifles chambered in this cartridge. Later on, the Jeffery Co. realized that the velocity could easily be increased, and now we have modern loads that toss a 400 grain pill at around 2400 fps which effectively duplicates the performance of the 416 Rigby and 416 Remington. The rifle was apparently a great sheep rifle as well (see the Chadwick ram).....
I say all of this to say that Norma and Vihtavouri powders should certainly get you to an acceptable velocity for a 400 grain Swift A-frame. Find a load that shoots accurately and gets you in the 2200-2300 fps range and you will have a rifle that will dispatch any animal on earth...and do it with style. Most importantly, before you take the handloads to hunt buff, lion, or elephant ensure those cartridges will all cycle smoothly from magazine to chamber, as well as eject from the rifle as well. Test every single one of them in the rifle you intend to bring.
Good luck with your load development and make sure to post the results. Some of us rifle and handloading cranks love to see the results....