Here is a report of a hunter that was written in a book
I hunted a giraffe with 80 foot-pounds (70 pounds draw weight, 30" draw length, 800gr @ 212fps, 210gr Silver flame BH, Ro=4.3). The broadhead required according to the model 88 foot-pounds (50 foot-pounds just getting into the chest cavity). The experiment was specifically designed to test the predicted penetration. This is not a chance I would normally take, but my PH was taking aim with me, and if the shot looked even slightly ineffective, he was waiting for the instruction "Shoot". But at 43 yards the hit was clean, just above the heart, and penetrated about 25" - no need for the .375. The giraffe went down after about 100Y. The predicted penetration was 29". This experiment again confirmed the model. (Note - hunting a giraffe again with this setup is NOT recommended, rather use 800gr at 90 foot-pounds!!!)
Larger game is generally slower to move, and 30Y is quite acceptable for the large antelopes. For Giraffe and buffalo, 40Y is not unrealistic. The maximum suggested hunting distance is not a function of the hunter's accuracy, but indeed of the animal's reaction time (and size of vital organs) vs. the speed of the arrow.
NB. At the generally accepted arrow velocity of 250fps, animals at 20Y have about 0.2 seconds to react to the sound and animals at 40Y about 0.4 seconds.
If the arrow mass is 800gr, arrow speed is 188fps, and Ro is 8lbs, the penetration is around 40 inches. According to the optimum recommendations on mass and velocity, this would qualify as a perfectly acceptable hunting arrow for all categories. In reality this velocity would provide the animals 0.280 and 0.580 seconds at 20 and 40 yards to react. This is in regards to reaction time, as (un)acceptable as shooting a 250fps arrow at an animal at 60+ Y. Therefore, the suggested decrease in maximum hunting range of arrows that does meet the optimum speed recommendation with the adjusted speed, but in reality is slower, is suggested in line with a reaction time of 0.2 to 0.4 seconds. Another factor plays a role in defining maximum distances. Arrows loose speed due to friction in air, roughly at about 1% per 10Y. An arrow at release may have 40ft.lbs energy but at 60Y it may only have 35ft.lbs (for 570gr at 195fps). Arrows shot to an elevated target loses speed more quickly in relation to the angle. Arrows shot to a downhill target loses speed much slower again. However, when staying within the recommended speeds, this effect is overshadowed by accuracy and reaction time compensations.
Hunting tips for above 800kg, buffalo, giraffe, hippo etc., a two bladed broadhead of at least 1.25" is suggested, without bleeder blades.
Zimbabwe regulations. Giraffe and Eland Minimum pull 35Kg or 77 pound min arrow weight 700gr (45 grams)