Thanks for helping me visualize how this works.
Experience:
Most of rifles I tested, or zeroed: (calibers 30, and similar) have zero at 50 and approximate zero at 100.
This means zero the rifle at 50 meters, check it at 100, it will be zero again.
Then you can increase the range by playing with point blank range, keeping trajectory loop within size of vital zone of animal you hunt.
Example:
My 30-06 has +3cm at 50 meters, +6 cm at 100 meters, zero at 200 meters (about)
next reference: 375 HH has external ballistic similar to 30-06. Just to give you idea of similarities of various caliber trajectories
If you are negative at 50, you will be more negative at any further distance.
If you are positive till 50, it is just matter establishing the second zero and distance
Practical advice.
If you want exact reference, for your specific load, get following data of your cartridge:
Muzzle velocity (measure by chrono).
(or muzzle velocity by factory, reduce by 10-20 feet per second from declared value on the box)
Bullet weight (provided by factory reference, or by your scale)
Bullet BC, ballistic coefficient. (provided by factory on the box)
Exact distance of scope to muzzle. (measure)
Then go to ballistic calculator on line, suggest
Hornady ballistic calculator (google this), enter above data for any distance and any zero, press enter and get calculated ballistic table
For example: try entering zero at 100, or zero at 200, etc, and get the idea of trajectory for any load you wish.
Then zero the rifle as per your preference.