JMO, but if you’re just going to hunt a dry climate and like traditional bluing and wood, the CZ or RSM are very nice. If you plan a hunt to humid areas such as Kodiak or southeastern coast of Alaska for brown bear, maybe even the lush wet jungles of Africa, then I’d suggest you look seriously at the stainless/synthetic stocked rifles. Some are made by Kimber, Sako, MRC, Winchester, Ruger and I believe Browning.
The only 458 Lott I Shot was last year while at PawPrints. The PH, Johan let me fire his which seemed very heavy and it wasn’t bad. But my recovery time for a second shot was substantially less than my 375 H&H. I’m 70 yo, 5’8” and 158lbs and it set me back pretty well.
Best of luck in your decision!