I used 110 grains of RL-15 with the 570-gr bullets (GSC FN and Barnes XLC, olde-style blue-coated)
in a 23" barreled .500 A2 for my hunting load.
Gave about 2450 fps MV (McGowen 1:10" twist, stainless, on a BRNO ZKK 602 in a McMillan stock).
Today I would choose Varget for better ThermoBallisticIndependence.
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That was iron-sighted and with the muzzle brake removed, just to be kind to my ears.
The 570-gr XLC broke an offside shoulder and the 5-1/2 y.o. bull turned to run on three legs.
Then the 570-gr GSC FN entered his rump and came out his throat, tail to tonsils, exited.
He dropped after two impacts at about 50 yards for each shot.
For my target load in a Ruger No. 1 .500 A2 with 27" barrel that I throated a little longer for the heavier 50 BMG bullets (McGowen 1:10" twist, stainless also)
IMR-4350 worked a charm.
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705-gr AAA Harlow bullet with 110 grains of that did about 2125 fps and
would put 3 bullets into 0.170" at 100 yards when I got lucky.
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A 5-mil holdover with that powder charge and the 750-gr Hornady A-Max would get me on paper at 942 yards, in a cow pasture.
I would choose H4350 for such plinking nowadays.
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