I'm a big fan of Grand Slams for most game. I have had great success using them at modest velocities out of a 30-06, all one shot kills on medium sized game with great penetration and expansion. The 200 grain .308 version is my favorite for black bear, unfortunately they have been discontinued. Fortunately, I have sourced three boxes and will be using them this fall. I'm not sure I'd use them for larger plains game as there are probably better choices. When I go back to Africa, I'll use Woodleigh or A Frames.