Have had FTF issues with CCI LR primers from a couple of different batches over the years. Only sorted the problem on the second occasion. As some have posted CCI primer cups are a harder material than other brands and require a sterner strike force for ignition. I FL size my brass and am careful re correct headspace which works well for primer brands ( in my case predominantly Federal ) other than CCI.
On my second episode with CCI FTF I tried to shoot the defective rounds 3 times and even with very obvious firing pin indentations on the primers they would just not ignite. I chatted to a gunsmith who explained a small headspace correction, relative to CCI primers, would likely solve the matter. So I backed off my FL die maybe around 1/8 to 1/4 turn and loaded rounds using 5 of the "defective" and retrieved FTF primers. The bolt did feel a little firmer on closing but every one of those primers ignited. So yep, definitely not defective primers.
However, my confidence in CCI primers remains diminished. I no longer use them in hunting rounds. Have since sold or given away what I had and stuck with Federal which, so far over several thousand shots, have never failed.