Your questions are exactly the recommendations an expert Reloader that knows nothing of double rifles would recommend. Those recommendations could cause injury to gun or shooter.
We have a particular recoil impulse, burn rate, and pressure curve that the original rifle was designed to endure. The original nitro-for-black load would have been stranded cordite. The closest thing we have to that powder in current production is IMR3031 and there is a conversion (don’t quote me, i think its 1.02:1 ratio) The only problem with it is that it will not come close to filling the case, thus you must use a wad to hold the powder against the primer for consistent ignition.
If it were me, I would not rely solely on pressure and try variety of powders, I would try to create a load that mimics the original behavior of stranded cordite nitro-for-black loads. This is what Ross Seyfried or Ken Owen would recommend. It has to be safe, it has to mimic original properties, and it has to regulate correctly…not easy to accomplish.
I’ve owned a 500 Nitro-For-Black and this was how my loads were developed.