After so many trips I finally found out the answer to your question. When I get on the plane I set my watch to Africa time and attempt to sleep accordingly.
I hope this can help safari travelers plan for a most successful trip.
This method is what I practiced, based on advice from my doctor in Dallas.
Travelled in the late1990s, traveling to Europe, Middle East, Africa once a month.
My doctor treated many AA international pilots and travelled a lot himself to his home in Dublin. He studied circadian rhythms carefully and the relationship with rapidly changing time zones,
Doc had a few recommendations:
1. When you get on the plane, set your watch to your destination time zone, and live and work by that schedule. Don't take a nap.
2. Eat a small meal/dinner 2 hours or so after wheels up (departing DFW around 4PM) 7–8-hour flight to London. Business class helped provide comfort, at least when British Airways had good service.
3. Take the sleep medicine after dinner (he had a specific drug regimen for me) and drink alcohol only in moderation. Couple of glasses of white wine was good for me. Drink a lot of water before sleep. Sleep for 5-6 hours.
4. When waking for breakfast, a couple of hours before landing, have a light breakfast. Some protein (eggs) worked for me and a couple cups of coffee.
Always awakened by the smell of the coffee brewing. just like on the farm as a kid.
Landed at 7 or 8 am, then go to work, all day, don't take a nap. Connecting flights just roll with it.
Usually the first couple of nights, I went to bed early, (9-10pm).
Heading home, going West, fatigue set in, and just rested for 4-5 days at home. Dealt with the jet lag, waking up at 3AM, working for a few hours.
Throughout 20 trips over, this has worked for me.
Everyone is individual in their travel needs, adjust accordingly.
Vaya con Dios.